Transcriptional regulation constrains the organization of genes on eukaryotic chromosomes
نویسندگان
چکیده
منابع مشابه
Transcriptional regulation constrains the organization of genes on eukaryotic chromosomes.
Genetic material in eukaryotes is tightly packaged in a hierarchical manner into multiple linear chromosomes within the nucleus. Although it is known that eukaryotic transcriptional regulation is complex and requires an intricate coordination of several molecular events both in space and time, whether the complexity of this process constrains genome organization is still unknown. Here, we prese...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0806317105